Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489581 | 0.94 | LMNA (0.59) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL9158246 | 0.85 | HSD17B10 (0.76) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL329365 | 0.85 | HSD17B10 (0.76) | HSD17B10LMNAGAAMAPTPOLB | |
| Water SCHEMBL9344643 | 0.83 | HSD17B10 (0.73) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL5945230 | 0.83 | HSD17B10 (0.58) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL4960001 | 0.79 | LMNA (0.71) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL16327448 | 0.79 | LMNA (0.61) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL9544647 | 0.79 | HSD17B10 (0.68) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL9330408 | 0.79 | HSD17B10 (0.74) | HSD17B10LMNAGAAMAPTPOLB | |
| SCHEMBL269329 | 0.78 | LMNA (0.80) | HSD17B10LMNAGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670581-A | Biphenyl compounds and process for producing the same | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-06-02 | — | — | US | claimed |