Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742007 | 0.89 | NPC1 (0.39) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30599590 | 0.87 | NPC1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL5176952 | 0.87 | NPC1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL5888063 | 0.84 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29520649 | 0.84 | ALDH1A1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6742012 | 0.82 | APEX1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL9299327 | 0.81 | MAPK14 (0.42) | ALDH1A1APEX1MAPK14CA1CA2 | |
| SCHEMBL2187400 | 0.79 | CA1 (0.37) | ALDH1A1APEX1CA1CA2CA9 | |
| SCHEMBL29444201 | 0.77 | APEX1 (0.35) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL9299329 | 0.77 | APEX1 (0.36) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672086-A | BLEND WITH POLYPHENYLENE ETHERS, PHOSPHOROUS COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-09 | — | — | US | disclosed |