Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778884 | 0.93 | ACE (0.55) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10783396 | 0.82 | ACE (0.72) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10779532 | 0.82 | ACE (0.64) | ACELMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL10972356 | 0.81 | ACE (0.61) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL683465 | 0.81 | ACE (0.73) | ACELMNASMN1; SMN2ABCB11ALOX15 | |
| Trifluoroacetic Acid SCHEMBL10971638 | 0.79 | ACE (0.70) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL682300 | 0.79 | ACE (0.76) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| Enalapril SCHEMBL8089096 | 0.79 | ACE (1.00) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| Enalapril SCHEMBL13933092 | 0.79 | ACE (1.00) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| Enalapril SCHEMBL13575793 | 0.79 | ACE (1.00) | ACELMNASMN1; SMN2ABCB11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | claimed |