Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778950 | 0.94 | ACE (0.55) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10968973 | 0.88 | ACE (0.57) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10972032 | 0.85 | ACE (0.74) | ACELMNASMN1; SMN2ACE2REN | |
| SCHEMBL11205558 | 0.84 | ACE (0.87) | ACELMNASMN1; SMN2 | |
| SCHEMBL11203453 | 0.84 | ACE (0.87) | ACELMNASMN1; SMN2 | |
| SCHEMBL11209208 | 0.84 | ACE (0.87) | ACELMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL10971638 | 0.82 | ACE (0.70) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10778971 | 0.82 | ACE (0.64) | ACELMNASMN1; SMN2 | |
| SCHEMBL10971911 | 0.81 | ACE (0.70) | ACELMNASMN1; SMN2ACE2REN | |
| SCHEMBL3368988 | 0.81 | ACE (0.74) | ACELMNASMN1; SMN2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | claimed |