Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078865 | 0.82 | MEN1 (0.52) | MAPK1ALDH1A1GAANPC1L3MBTL1 | |
| SCHEMBL16063426 | 0.81 | CNR1 (0.54) | GRM5MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL1076424 | 0.74 | TSHR (0.51) | ALDH1A1GAAL3MBTL1LMNAHTR2A | |
| SCHEMBL24137329 | 0.73 | KDM1A (0.69) | — | |
| SCHEMBL1079479 | 0.72 | PIK3R2 (0.51) | GRM5MAPK1GAAPARP1PARP2 | |
| SCHEMBL1080644 | 0.71 | HTR2A (0.49) | ALDH1A1NPC1CSNK2A1MEN1KMT2A | |
| SCHEMBL28668013 | 0.71 | NPC1 (0.51) | MAPK1ALDH1A1GAANPC1CA1 | |
| SCHEMBL21068989 | 0.70 | KDM1A (0.43) | GRM5ALDH1A1GAAMAPT | |
| SCHEMBL15004825 | 0.70 | PARP10 (0.52) | MAPK1ALDH1A1GAANPC1L3MBTL1 | |
| SCHEMBL4961512 | 0.70 | CNR1 (0.55) | GRM5ALDH1A1GAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |