Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.49 |
| ▸ | HTR2C | P28335 | 9/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404260 | 0.77 | CNR2 (0.67) | HTR2AHTR2CSLC6A4CYP2D6CYP2C9 | |
| SCHEMBL5004569 | 0.74 | KDM4E (0.57) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16063426 | 0.73 | CNR1 (0.54) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1079479 | 0.73 | PIK3R2 (0.51) | HTR2AHTR2CSLC6A4CYP2D6CYP2C9 | |
| SCHEMBL1077899 | 0.71 | GRM5 (0.59) | HTR2AHTR2CSLC6A4NPC1RAB9A | |
| SCHEMBL21068989 | 0.71 | KDM1A (0.43) | ALDH1A1KDM4E | |
| SCHEMBL20637470 | 0.68 | BRD9 (0.45) | TSHRPOLBALDH1A1KDM4EBRD9 | |
| SCHEMBL1077940 | 0.67 | NOTUM (0.46) | HTR2AHTR2CSLC6A4MEN1KMT2A | |
| SCHEMBL20637402 | 0.67 | DYRK1A (0.49) | TSHRNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL20637431 | 0.67 | TDP1 (0.49) | TSHRNPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |