Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.45 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10779433 | 0.95 | ACE (0.54) | ACELMNAALOX5SMN1; SMN2CYP2C19 | |
| SCHEMBL10779618 | 0.91 | ACE (0.62) | ACELMNAALOX5SMN1; SMN2CYP2C19 | |
| SCHEMBL7325826 | 0.85 | ACE (0.61) | ACELMNASMN1; SMN2CYP2C19DPP3 | |
| SCHEMBL7325822 | 0.85 | ACE (0.61) | ACELMNASMN1; SMN2CYP2C19DPP3 | |
| SCHEMBL10781418 | 0.85 | ACE (0.64) | ACEALOX5CYP2C19DPP3GABRA1 | |
| SCHEMBL7321737 | 0.84 | ACE (0.70) | ACELMNASMN1; SMN2CYP2C19DPP3 | |
| SCHEMBL10779345 | 0.84 | ACE (0.54) | ACELMNAALOX5SMN1; SMN2GABRA1 | |
| Trifluoroacetic Acid SCHEMBL10781948 | 0.83 | ACE (0.45) | ACEALOX5CYP2C19DPP3GABRA1 | |
| SCHEMBL10971911 | 0.83 | ACE (0.70) | ACELMNASMN1; SMN2ACE2REN | |
| SCHEMBL10782036 | 0.82 | ALOX5 (0.50) | ACELMNAALOX5SMN1; SMN2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | claimed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | claimed |
| EP-0084941-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-11 | — | — | EP | disclosed |
| US-4528282-A | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0084941-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-03 | — | — | EP | disclosed |