Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779581 | 0.91 | DRD4 (0.54) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10780851 | 0.89 | DRD4 (0.50) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL10784337 | 0.89 | DRD4 (0.52) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| Water SCHEMBL10785495 | 0.89 | DRD4 (0.49) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| Isopropyl Alcohol SCHEMBL11011590 | 0.87 | DRD4 (0.50) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10779806 | 0.86 | DRD4 (0.52) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10780432 | 0.86 | DRD4 (0.55) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL10779897 | 0.85 | DRD4 (0.52) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10790438 | 0.85 | DRD4 (0.60) | DRD4SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10780527 | 0.84 | DRD4 (0.52) | DRD4SIGMAR1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150505-B1 | 3-INDOLECARBOXAMIDE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |
| US-4581355-A | HYPOTENSIVE AGENTS, LIPOXYGENASE INHIBITORS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0150505-A2 | 3-Indolecarboxamide compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-08-07 | — | — | EP | disclosed |