Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | RARG | P13631 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396121 | 0.86 | MEN1 (0.51) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL4606457 | 0.83 | MEN1 (0.45) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL11084834 | 0.81 | ALOX5AP (0.49) | TP53KMT2AMEN1GAAPOLB | |
| SCHEMBL23774956 | 0.79 | PTPN11 (0.48) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL26624850 | 0.79 | PTPN11 (0.48) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL31680593 | 0.79 | PTPN11 (0.48) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL26624844 | 0.79 | PTPN11 (0.48) | TRPA1TP53TDP1KMT2AMEN1 | |
| SCHEMBL11816339 | 0.77 | ALDH1A1 (0.40) | GAAALDH1A1MAPTALOX12LMNA | |
| SCHEMBL13004822 | 0.74 | MEN1 (0.44) | TP53KMT2AMEN1GAAPOLB | |
| SCHEMBL19150643 | 0.74 | KMT2A (0.54) | TP53KMT2AMEN1POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126193-B1 | BIS-(NORBORNYL OR SUBSTITUTED NORBORNYL) DERIVATIVES OF A PHENOL OR A PHENYLAMINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING SAME | THE DOW CHEMICAL COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| US-4548976-A | Bis-(norbornyl or substituted norbornyl) derivatives of a phenol or a phenylamine, process for their preparation and compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0126193-A1 | Bis-(norbornyl or substituted norbornyl) derivatives of a phenol or a phenylamine, process for their preparation and compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1984-11-28 | — | — | EP | disclosed |