Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337039 | 0.91 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL11126908 | 0.89 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Bicarbonate SCHEMBL10780457 | 0.85 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL15322926 | 0.85 | LMNA (0.44) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL3701304 | 0.83 | LMNA (0.44) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2904704 | 0.82 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2904697 | 0.82 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL44490 | 0.82 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28170840 | 0.81 | LMNA (0.42) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Alcohol SCHEMBL20504373 | 0.80 | LMNA (0.53) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4658041-A | EQUILIBRIUM INTERCHANGE OF ALKYL HALIDES AND AN ALKYL CARBONATE USING A BASIC CATALYST | THE DOW CHEMICAL COMPANY (US) | 1987-04-14 | — | — | US | disclosed |