Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455965 | 0.83 | NPC1 (0.48) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10780706 | 0.79 | CYP3A4 (0.62) | MAPTCYP3A4TSHRHTTMAOB | |
| SCHEMBL4010734 | 0.77 | HSD11B1 (0.41) | POLBAPEX1NPC1MAPTRAB9A | |
| SCHEMBL2630704 | 0.76 | POLB (0.46) | POLBAPEX1NPC1MAPTRAB9A | |
| SCHEMBL29997409 | 0.76 | POLB (0.46) | POLBAPEX1NPC1MAPTRAB9A | |
| SCHEMBL690412 | 0.76 | POLB (0.46) | POLBAPEX1NPC1MAPTRAB9A | |
| SCHEMBL3151867 | 0.76 | KCNK3 (0.40) | SCN9ACYP3A4TSHRALDH1A1 | |
| SCHEMBL1902931 | 0.76 | GAA (0.46) | POLBNPC1MAPTRAB9AHPGD | |
| SCHEMBL17191634 | 0.75 | SRC (0.40) | MAPTHPGDSMN1; SMN2KMT2ASCN9A | |
| SCHEMBL3146063 | 0.75 | CYP3A4 (0.36) | NPC1MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695646-A | OXYQUINOLINECARBOXYLIC ACID INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |