Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777233 | 0.88 | TDP1 (0.51) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11259245 | 0.80 | NR1I2 (0.66) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10779497 | 0.80 | NR1I2 (0.66) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10914907 | 0.80 | MAPT (0.64) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10830927 | 0.76 | PTGS1 (0.40) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10830929 | 0.76 | PTGS1 (0.40) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL8371361 | 0.75 | TDP1 (0.44) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11212601 | 0.74 | NR1I2 (0.50) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL4809163 | 0.74 | NR1I2 (0.50) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL4809193 | 0.74 | NR1I2 (0.50) | TDP1MAPTNR1I2SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4680390-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4520194-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| US-4278671-A | ANTIBIOTICS, BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-14 | — | — | US | disclosed |