Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780914 | 1.00 | KDM4E (0.53) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL8665323 | 0.82 | KDM4E (0.54) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL6557536 | 0.82 | KDM4E (0.54) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL2317476 | 0.80 | KDM4E (0.57) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL27588810 | 0.77 | KDM4E (0.50) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL8981613 | 0.76 | CA9 (0.40) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL12013645 | 0.75 | KMT2A (0.65) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL13013116 | 0.75 | KMT2A (0.65) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL10609912 | 0.75 | KMT2A (0.65) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL10609916 | 0.75 | KMT2A (0.65) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4655783-A | COPPER COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0200843-A1 | Process for the photochemical stabilisation of undyed and dyed polyamide fibrous material and its mixtures | CIBA-GEIGY AG (CH) | 1986-11-12 | — | — | EP | disclosed |