Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665323 | 1.00 | KDM4E (0.54) | KDM4EMAPTHTTHPGDMGLL | |
| SCHEMBL10780914 | 0.82 | KDM4E (0.53) | KDM4EMAPTHTTHPGDMEN1 | |
| SCHEMBL2317476 | 0.82 | KDM4E (0.57) | KDM4EMAPTHTTHPGDMEN1 | |
| SCHEMBL10780902 | 0.82 | KDM4E (0.53) | KDM4EMAPTHTTHPGDMEN1 | |
| SCHEMBL363988 | 0.79 | ATM (0.47) | HPGDMGLLMEN1KMT2AGAA | |
| SCHEMBL27588810 | 0.79 | KDM4E (0.50) | KDM4EMAPTHTTHPGDMEN1 | |
| SCHEMBL24661575 | 0.78 | SMN1; SMN2 (0.43) | HPGDMGLLNPC1ALDH1A1ATM | |
| SCHEMBL15164586 | 0.78 | SMN1; SMN2 (0.43) | HPGDMGLLNPC1ALDH1A1ATM | |
| SCHEMBL15164588 | 0.78 | MGLL (0.50) | KDM4EMAPTHPGDMGLLMEN1 | |
| SCHEMBL12253472 | 0.78 | ALDH1A1 (0.46) | KDM4EMAPTHTTHPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243000-B | A kind of Valinamide carbamate derivatives of base containing propynyloxy and application | 南开大学 | 2017-12-05 | — | — | CN | disclosed |
| CN-106243000-A | A kind of Valinamide carbamate derivatives containing propargyl epoxide and application | 南开大学 | 2016-12-21 | — | — | CN | disclosed |
| EP-1098912-B1 | INHIBITING SCALE IN VINYL MONOMER POLYMERIZATION | OXY VINYLS LP (US) | 2004-03-10 | — | — | EP | disclosed |
| US-6506854-B2 | Antiscaling agent consists of a solvent; a reaction product of an aromatic compound containing benzene or napthalene ring substituted with hydroxy, mercaptan, sulfide etc, a carbonyl monomer and a thiourea; sodium hydroxide and sodium chloride | OCCIDENTAL CHEMICAL CORPORATION | 2003-01-14 | — | — | US | disclosed |
| US-20020015692-A1 | Inhibiting scale in vinyl monomer polymerization | OCCIDENTAL CHEMICAL CORP. | 2002-02-07 | — | — | US | disclosed |
| US-6300427-B1 | USED TO PREVENT FORMATION OF SCALE ON REACTOR SURFACES | OCCIDENTAL CHEMICAL CORPORATION | 2001-10-09 | — | — | US | disclosed |
| EP-1098912-A1 | INHIBITING SCALE IN VINYL MONOMER POLYMERIZATION | Oxy Vinyls L.P. (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6114476-A | CONTACTING MONOMER WITH TERPOLYMER WHICH COMPRISES THE CONDENSATION REACTION PRODUCT OF AN AROMATIC COMPOUND, A CARBONYL COMPOUND, AND A THIOUREA | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-09-05 | — | — | US | disclosed |
| WO-2000009570-A1 | INHIBITING SCALE IN VINYL MONOMER POLYMERIZATION | OXY VINYLS, L.P. (US) | 2000-02-24 | — | — | WO | disclosed |
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | disclosed |
| WO-1995001157-A1 | USE OF HYDROXYPHENYL OXIMES AS CHELATING PHOTOPROTECTANTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020015692-A1 | Inhibiting scale in vinyl monomer polymerization | TST, RTCB, ALK | KDM4E 1790/4885MAPT 3974/4885HTT 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.