Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377692 | 0.97 | ALDH1A1 (0.41) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL29039595 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL16317252 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL22295830 | 0.79 | ALDH1A1 (0.33) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL14518026 | 0.76 | ALDH1A1 (0.31) | ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL31705515 | 0.76 | MGAM (0.41) | ALDH1A1MAPT | |
| SCHEMBL2474496 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KEAP1NFE2L2HCAR2MAPT | |
| SCHEMBL28352138 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KEAP1NFE2L2HCAR2 | |
| SCHEMBL28352291 | 0.73 | — | — | |
| SCHEMBL27959269 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KEAP1NFE2L2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665218-A | Method for the preparation of alkoxymethylene compounds of acetic esters and substituted acetic esters | DYNAMIT NOBEL AG (DE) | 1987-05-12 | — | — | US | disclosed |