Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 6/20 | 0.71 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.71 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.71 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.71 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781148 | 1.00 | SSTR1 (0.71) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL11066517 | 0.95 | SSTR1 (0.64) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL8577146 | 0.92 | SSTR4 (0.63) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL5961352 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13204994 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL12896361 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL3752664 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13591468 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL15338590 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1957129 | 0.89 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103877-B1 | PHOSPHATE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
| US-4481196-A | ANTI-FIBROSARCOMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-06 | — | — | US | disclosed |
| EP-0103877-A1 | Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-28 | — | — | EP | disclosed |