SCHEMBL5961352

SCHEMBL5961352

COC1O[C@@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.70
SSTR2 P30874 1/20 0.70
SSTR4 P31391 1/20 0.70
SSTR3 P32745 1/20 0.70
SSTR5 P35346 1/20 0.70
NT5E P21589 1/20 0.55
GJB2 P29033 1/20 0.54
PTPN1 P18031 9/20 0.54
PTPN2 P17706 4/20 0.54
BCHE P06276 1/20 0.54
CDC25B P30305 6/20 0.51
HTR1A P08908 1/20 0.50
PTPN6 P29350 2/20 0.49
PTPN11 Q06124 2/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31491488 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL15338590 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL1957129 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3752668 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13204994 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL13591468 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL12896361 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL3752664 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6872203 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL30928985 1.00 SSTR1 (0.70) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283211-B1 L-Nucleosides for the treatment of hepatitis B-virus and Epstein-barr virus UNIV GEORGIA RES FOUND (US) 2006-06-07 EP disclosed
EP-0748330-B1 L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS UNIV GEORGIA RES FOUND (US) 2003-04-02 EP disclosed
EP-1283211-A2 L-Nucleosides for the treatment of hepatitis B-virus and Epstein-barr virus THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2003-02-12 EP disclosed
US-5808040-A VIRICIDES YALE UNIVERSITY (US) 1998-09-15 US disclosed
US-5753789-A Oligonucleotides containing L-nucleosides YALE UNIVERSITY (US) 1998-05-19 US disclosed
US-5587362-A VIRICIDES FOR HEPATITIS VIRUS AND EPSTEIN-BAR VIRUS UNIV. OF GA RESEARCH FOUNDATION (US) 1996-12-24 US disclosed
EP-0748330-A1 L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-12-18 EP disclosed
US-5567688-A ADMINISTERING SPECIFIED ENANTIOMORPH TO HUMAN INFECTED WITH HEPATITIS B VIRUS UNIV. OF GA RESEARCH FOUNDATION (US) 1996-10-22 US disclosed
US-5565438-A L-nucleosides for the treatment of epstein-bar virus UNIVERSITY OF GA RESEARCH FOUNDATION (US) 1996-10-15 US disclosed
WO-1995020595-A1 L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1995-08-03 WO disclosed