Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE9A | O76083 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349377 | 0.88 | KDM4E (0.49) | MAPTNPC1ALDH1A1GAAKDM4E | |
| SCHEMBL10787999 | 0.88 | PDE4B (0.51) | MAPTNPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10781983 | 0.88 | MAPT (0.52) | MAPTNPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15349420 | 0.86 | ALDH1A1 (0.52) | MAPTNPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10781736 | 0.86 | MAPT (0.54) | MAPTNPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18181685 | 0.86 | KDM4E (0.51) | MAPTNPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15349516 | 0.85 | KDM4E (0.47) | MAPTNPC1ALDH1A1GAAKDM4E | |
| SCHEMBL15358441 | 0.85 | KDM4E (0.47) | MAPTNPC1ALDH1A1GAAKDM4E | |
| SCHEMBL10786798 | 0.85 | KDM4E (0.48) | MAPTNPC1ALDH1A1GAAKDM4E | |
| SCHEMBL10786146 | 0.85 | MAPT (0.54) | MAPTNPC1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144730-B1 | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0144730-A1 | 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |