SCHEMBL10784100

SCHEMBL10784100

O=C(O)NS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.58
FLT1 P17948 1/20 0.58
FLT4 P35916 1/20 0.58
KDR P35968 1/20 0.58
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
ALDH1A1 P00352 2/20 0.53
PGR P06401 1/20 0.49
GAA P10253 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CA12 O43570 4/20 0.48
CA1 P00915 4/20 0.48
CA9 Q16790 4/20 0.48
CA2 P00918 3/20 0.48
ITGAV P06756 1/20 0.48
EDNRA P25101 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3954909 1.00 POLB (0.58) POLBFLT1FLT4KDRSLC1A3
SCHEMBL6099940 0.85 FLT1 (0.46) POLBFLT1FLT4KDRSLC1A3
SCHEMBL29109030 0.84 FLT1 (0.61) POLBFLT1FLT4KDRSLC1A3
SCHEMBL2351670 0.83 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
SCHEMBL19630968 0.83 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
SCHEMBL29543742 0.83 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
SCHEMBL30754385 0.83 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
Hydrochloric Acid SCHEMBL31556307 0.82 FLT1 (0.60) POLBFLT1FLT4KDRSLC1A3
SCHEMBL9846425 0.81 POLB (0.54) POLBFLT1FLT4KDRSLC1A3
SCHEMBL3335057 0.80 POLB (0.54) POLBFLT1FLT4KDRSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107624-B1 PROCESS FOR THE PRODUCTION OF HERBICIDAL AND PLANT GROWTH REGULATING SULFONYL UREAS CIBA-GEIGY AG (CH) 1987-05-20 EP claimed