SCHEMBL2351670

SCHEMBL2351670

NC(=O)NS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
FLT1 P17948 1/20 0.56
FLT4 P35916 1/20 0.56
KDR P35968 1/20 0.56
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA9 Q16790 3/20 0.50
ALDH1A1 P00352 2/20 0.48
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PGR P06401 1/20 0.44
ITGAV P06756 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29543742 1.00 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
SCHEMBL8927141 0.86 PTGES2 (0.53) POLBFLT1FLT4KDRTSHR
SCHEMBL1268486 0.84 POLB (0.51) POLBFLT1FLT4KDRSLC1A3
SCHEMBL3954909 0.83 POLB (0.58) POLBFLT1FLT4KDRSLC1A3
SCHEMBL10784100 0.83 POLB (0.58) POLBFLT1FLT4KDRSLC1A3
SCHEMBL19630968 0.81 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
SCHEMBL30754385 0.81 POLB (0.56) POLBFLT1FLT4KDRSLC1A3
Acetic Acid SCHEMBL28282467 0.80 POLB (0.49) POLBFLT1FLT4KDRSLC1A3
SCHEMBL10667500 0.79 MEN1 (0.44) POLBFLT1FLT4KDRCA12
SCHEMBL10729804 0.79 CA1 (0.55) POLBFLT1FLT4KDRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2024-04-18 US claimed
CN-117813004-A Auxin herbicide and application method thereof 科迪华农业科技有限责任公司 2024-04-02 CN claimed
EP-2967035-B1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING PYRIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR USE IN CORN (MAIZE) CORTEVA AGRISCIENCE LLC (US) 2022-12-14 EP claimed
CN-105208856-B Herbicidal combinations for the safe comprising the formic acid derivates of pyridine 2 of corn (corn) 美国陶氏益农公司 2017-12-01 CN claimed
US-9493782-B2 Inducible promoter sequences for regulated expression and methods of use PIONEER HI-BRED INTERNATIONAL, INC. (US) 2016-11-15 US claimed
EP-2967035-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING PYRIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR USE IN CORN (MAIZE Dow AgroSciences LLC (US) 2016-01-20 EP claimed
CN-105208856-A Safened herbicidal compositions including pyridine-2-carboxylic acid derivatives for use in corn (maize) DOW AGROSCIENCES LLC 2015-12-30 CN claimed
CN-104487577-A Inducible promoter sequences for regulating expression and methods of use PIONEER HI BRED INT 2015-04-01 CN claimed
WO-2014150740-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING PYRIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR USE IN CORN (MAIZE DOW AGROSCIENCES LLC (US) 2014-09-25 WO claimed
US-20140274704-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF FOR USE IN CORN (MAIZE) DOW AGROSCIENCES LLC (US) 2014-09-18 US claimed
WO-2013173535-A2 INDUCIBLE PROMOTER SEQUENCES FOR REGULATED EXPRESSION AND METHODS OF USE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-11-21 WO claimed
US-20130312137-A1 INDUCIBLE PROMOTER SEQUENCES FOR REGULATED EXPRESSION AND METHODS OF USE PIONEER HI-BRED INTERNATIONAL INC (US) 2013-11-21 US claimed
US-5608143-A NUCLEIC ACID PROMOTER FRAGMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US claimed
US-5364780-A Genetic engineering with DNA and promoters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-15 US claimed
EP-0463056-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP claimed
WO-1990011361-A1 EXTERNAL REGULATION OF GENE EXPRESSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 WO claimed
EP-0388186-A1 External regulation of gene expression E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-19 EP claimed
US-4645527-A PLANT SAFENING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-24 US claimed
US-20260083131-A1 AN HERBICIDAL COMBINATION, COMPOSITION AND METHOD OF CONTROLLING WEEDS USING THE SAME UPL MAURITIUS LTD (MU) 2026-03-26 US disclosed
US-4645527-A PLANT SAFENING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF DDT, HACL2, ALAD POLB 2854/4885FLT1 1943/4885FLT4 848/4885
US-20260083131-A1 AN HERBICIDAL COMBINATION, COMPOSITION AND METHOD OF CONTROLLING WEEDS USING THE SAME GSS, GLS2, WEE1 POLB 2878/4885FLT1 1632/4885FLT4 1008/4885
US-20140274704-A1 SAFENED HERBICIDAL COMPOSITIONS INCLUDING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF FOR USE IN CORN (MAIZE) DDT, DDC, DBF4 POLB 1687/4885FLT1 1377/4885FLT4 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.