Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786379 | 0.78 | CYP3A4 (0.39) | PABPC1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL11721046 | 0.76 | PABPC1 (0.39) | PABPC1TDP1 | |
| SCHEMBL11316324 | 0.75 | TP53 (0.33) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11404420 | 0.68 | PDE10A (0.39) | PABPC1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL11322932 | 0.66 | CYP3A4 (0.38) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11743793 | 0.66 | — | — | |
| SCHEMBL10787311 | 0.65 | CYP3A4 (0.35) | PABPC1CYP3A4TSHRMAPK1 | |
| SCHEMBL13525197 | 0.65 | CYP3A4 (0.41) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11789695 | 0.65 | TDP1 (0.41) | PABPC1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL1153823 | 0.64 | CYP3A4 (0.36) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4246181-A | HAIR DYE | L'OREAL (FR) | 1981-01-20 | — | — | US | disclosed |
| US-3953508-A | Diphenylamines for dyeing keratinous fibers | L'OREAL (FR) | 1976-04-27 | — | — | US | disclosed |