SCHEMBL10784273

SCHEMBL10784273

CCS(=O)(=O)C(C)C(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.39
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6030449 0.78
SCHEMBL8624021 0.76 SMYD3 (0.40) SMYD3ALDH1A1
SCHEMBL17189654 0.76 SMYD3 (0.40) SMYD3ALDH1A1
SCHEMBL4766616 0.74 SMYD3 (0.43) SMYD3
SCHEMBL9626465 0.72
SCHEMBL10500132 0.72
SCHEMBL10885860 0.72
SCHEMBL10791502 0.70
SCHEMBL2015431 0.70 ALDH1A1 (0.42) SMYD3ALDH1A1
SCHEMBL6030442 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3472159-A1 TETRAHYDRO-PYRIDO[3,4-b]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF F. Hoffmann-La Roche AG (CH) 2019-04-24 EP disclosed
WO-2017216280-A1 TETRAHYDRO-PYRIDO[3,4-b]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF F. HOFFMANN-LA ROCHE AG (CH) 2017-12-21 WO disclosed
EP-0125763-B1 MEDIUM FOR ELECTROPHORESIS FUJI PHOTO FILM CO., LTD. (JP) 1987-05-06 EP disclosed
EP-0126639-A2 Element for electrophoresis Director of the Finance Division Minister's Secretariat Science and Technology Agency (JP) 1984-11-28 EP disclosed
EP-0126638-A2 Element for electrophoresis FUJI PHOTO FILM CO., LTD. (JP) 1984-11-28 EP disclosed
EP-0125763-A1 Medium for electrophoresis FUJI PHOTO FILM CO., LTD. (JP) 1984-11-21 EP disclosed
EP-0119808-A2 Element for electrophoresis Director of the Finance Division Minister's Secretariat Science and Technology Agency (JP) 1984-09-26 EP disclosed
EP-0119090-A2 Element for electrophoresis FUJI PHOTO FILM CO., LTD. (JP) 1984-09-19 EP disclosed