Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010942 | 0.86 | PTPN11 (0.53) | CNR2TSHRCYP3A4CYP2D6PTPN11 | |
| SCHEMBL17490620 | 0.81 | CYP2D6 (0.54) | CNR2SMN1; SMN2CYP3A4CYP2D6NPC1 | |
| SCHEMBL10784333 | 0.78 | BACE1 (0.42) | SYKLMNAHTTCNR2TSHR | |
| SCHEMBL28158844 | 0.77 | SYK (0.59) | SYKSMN1; SMN2MAPTL3MBTL1HPGD | |
| SCHEMBL11086322 | 0.76 | PPARA (0.60) | SYKTSHRSMN1; SMN2PTGDR2BACE1 | |
| Nitrogen SCHEMBL11326058 | 0.76 | NQO1 (0.50) | SYKTSHRSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL14354863 | 0.76 | CYP2D6 (0.51) | SMN1; SMN2MAPTL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL19612285 | 0.75 | MAPT (0.53) | LMNAHTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL8940719 | 0.74 | NR5A1 (0.49) | CNR2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL22561127 | 0.74 | CNR2 (0.43) | SYKLMNAHTTCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080241-B1 | DIAZOTYPE MATERIAL | Océ-Nederland B.V. (NL) | 1987-09-09 | — | — | EP | disclosed |