Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940667 | 0.92 | NR5A1 (0.51) | NR5A1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9699819 | 0.83 | SMPD1 (0.56) | NR5A1CYSLTR2CYSLTR1ESR1THRA | |
| SCHEMBL9698459 | 0.83 | SMPD1 (0.56) | NR5A1CYSLTR2CYSLTR1ESR1THRA | |
| SCHEMBL9698566 | 0.83 | NR5A1 (0.57) | NR5A1CYSLTR2CYSLTR1ESR1PLA2G4B | |
| SCHEMBL8704571 | 0.83 | SMPD1 (0.56) | NR5A1CYSLTR2CYSLTR1ESR1THRA | |
| SCHEMBL9698477 | 0.83 | NR5A1 (0.57) | NR5A1CYSLTR2CYSLTR1ESR1PLA2G4B | |
| SCHEMBL14330220 | 0.81 | SMPD1 (0.54) | NR5A1CYSLTR2CYSLTR1ESR1MEN1 | |
| SCHEMBL8943391 | 0.80 | PTPN11 (0.56) | NR5A1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9735320 | 0.80 | PTPN11 (0.56) | NR5A1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9333938 | 0.80 | PTPN11 (0.56) | NR5A1MEN1NPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |