Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.39 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538653 | 0.70 | PRSS1 (0.58) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL8958172 | 0.70 | BACE1 (0.50) | KMT2AMEN1MMP2MMP3MMP9 | |
| SCHEMBL10781287 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL542592 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL10911326 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL10908827 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL727008 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL10953095 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL10959370 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL726250 | 0.69 | PRSS1 (0.60) | KMT2AMEN1KDM4ERECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668619-A | MATRICES, ANTIBODIES, BINDING PROTEINS, LABELS | MILES LABORATORIES, INC. (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0051213-B1 | HOMOGENEOUS SPECIFIC BINDING ASSAY DEVICE, METHOD FOR PREPARING IT AND ANALYTICAL METHOD USING THE DEVICE | MILES LABORATORIES, INC. (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4447529-A | IMMUNOASSAY; AMINOGLYCOSIDE ANTIBIOTICS; STRIPS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4366243-A | POLYVINYL ALCOHOL, ALBUMIN | MILES LABORATORIES, INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4362697-A | Homogeneous specific binding assay test device having copolymer enhancing substance | MILES LABORATORIES, INC. (US) | 1982-12-07 | — | — | US | disclosed |
| EP-0051213-A1 | Homogeneous specific binding assay device, method for preparing it and analytical method using the device | MILES LABORATORIES, INC. (US) | 1982-05-12 | — | — | EP | disclosed |