Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7771150 | 0.82 | MMP2 (0.41) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL6587747 | 0.77 | BACE1 (0.43) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL8172406 | 0.77 | BACE1 (0.49) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL8162305 | 0.77 | BACE1 (0.49) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL6601819 | 0.77 | BACE1 (0.49) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL8175293 | 0.76 | BACE1 (0.51) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL2980975 | 0.71 | BACE1 (0.61) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL3484547 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL14625445 | 0.70 | BACE1 (0.55) | BACE1BACE2KMT2ALMNAGLA | |
| SCHEMBL10784347 | 0.70 | KMT2A (0.42) | BACE1BACE2KMT2ALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |