Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629130 | 0.97 | MAPT (0.33) | MAPT | |
| SCHEMBL1143576 | 0.81 | KDM4E (0.35) | — | |
| SCHEMBL11777503 | 0.79 | MAPT (0.33) | MAPT | |
| Calcium SCHEMBL30118873 | 0.78 | KDM4E (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL1478513 | 0.78 | KDM4E (0.33) | — | |
| SCHEMBL1395074 | 0.77 | — | — | |
| SCHEMBL17077306 | 0.76 | GPR84 (0.33) | — | |
| SCHEMBL9352961 | 0.76 | PPARD (0.30) | — | |
| SCHEMBL10298217 | 0.71 | MAPT (0.38) | MAPT | |
| SCHEMBL3337765 | 0.70 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096931-B1 | RADIOGRAPHIC IMAGING AGENTS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1987-03-25 | — | — | EP | claimed |
| EP-0096931-B1 | RADIOGRAPHIC IMAGING AGENTS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4504463-A | DIPHOSPHONATE, STANNOUS SALT | MALLINCKRODT, INC. (US) | 1985-03-12 | — | — | US | disclosed |
| EP-0096931-A2 | Radiographic imaging agents | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1983-12-28 | — | — | EP | disclosed |
| EP-0096932-A2 | Process for making a lyophilized product for use in skeletal imaging | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1983-12-28 | — | — | EP | disclosed |