Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ATF1 | P18846 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363611 | 0.91 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL10362994 | 0.90 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4EHPGDIDO1 | |
| SCHEMBL10364782 | 0.87 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KDM4EHPGDIDO1 | |
| SCHEMBL10362995 | 0.86 | KDM4E (0.40) | ALDH1A1L3MBTL1KDM4EHPGDIDO1 | |
| SCHEMBL10364605 | 0.86 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4EHPGDIDO1 | |
| SCHEMBL10362921 | 0.85 | NR1H2 (0.48) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL10869012 | 0.84 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL10351657 | 0.83 | KDM4E (0.44) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL10363030 | 0.81 | KDM4E (0.47) | ALDH1A1L3MBTL1KDM4EHPGDIDO1 | |
| SCHEMBL22093090 | 0.80 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4655816-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0181852-A1 | Substituted 2,6-substituted pyridine compounds | Monsanto Company (US) | 1986-05-21 | — | — | EP | disclosed |