Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667065 | 0.90 | LCK (0.46) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL418559 | 0.90 | LCK (0.46) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7861470 | 0.87 | LCK (0.44) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL18912879 | 0.87 | LCK (0.44) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL26713010 | 0.85 | DNM1 (0.46) | LCKDNM1MEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL10786110 | 0.85 | DNM1 (0.43) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL2856760 | 0.85 | LCK (0.48) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL667868 | 0.82 | DNM1 (0.48) | LCKDNM1MEN1KMT2AALDH1A1 | |
| Ethylenediamine SCHEMBL11394055 | 0.82 | DNM1 (0.45) | LCKDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL4432484 | 0.80 | DNM1 (0.52) | LCKDNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668810-A | DIAMINE PHENOXIDE COMPLEXES | GENERAL ELECTRIC COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4587327-A | Method for preparing polyphenylene oxide with copper (I) complex catalysts | GENERAL ELECTRIC COMPANY (US) | 1986-05-06 | — | — | US | disclosed |