Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.56 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786135 | 1.00 | ACE (0.56) | ACELTA4HLMNAACE2 | |
| SCHEMBL11313252 | 0.84 | ACE (0.56) | ACELTA4HLMNAACE2 | |
| SCHEMBL11313236 | 0.84 | ACE (0.56) | ACELTA4HLMNAACE2 | |
| SCHEMBL7365884 | 0.84 | ACE (0.61) | ACEACE2 | |
| SCHEMBL7361792 | 0.84 | ACE (0.61) | ACEACE2 | |
| SCHEMBL7334469 | 0.82 | ACE (0.65) | ACELTA4HLMNAACE2 | |
| SCHEMBL7334467 | 0.82 | ACE (0.65) | ACELTA4HLMNAACE2 | |
| SCHEMBL6438290 | 0.81 | ACE (0.65) | ACELTA4HLMNAACE2 | |
| SCHEMBL6438293 | 0.81 | ACE (0.65) | ACELTA4HLMNAACE2 | |
| SCHEMBL6436563 | 0.81 | ACE (0.65) | ACELTA4HLMNAACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670541-A | Use of diamino alcohols as analgesic agents | E. R. SQUIBB & SONS, INC. (US) | 1987-06-02 | — | — | US | disclosed |
| US-4552866-A | Use of diamino alcohols as analgesic agents | E. R. SQUIBB & SONS, INC. (US) | 1985-11-12 | — | — | US | disclosed |