Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165218 | 0.84 | KMT2A (0.51) | IDO1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL780242 | 0.81 | SMN1; SMN2 (0.61) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL11280915 | 0.79 | SMN1; SMN2 (0.51) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL1094971 | 0.79 | NPC1 (0.35) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL28052498 | 0.78 | NPC1 (0.34) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL31456653 | 0.76 | SMN1; SMN2 (0.43) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL30189802 | 0.76 | SMN1; SMN2 (0.51) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL21983970 | 0.76 | PIK3CA (0.54) | SMN1; SMN2KMT2ANPC1RAB9AGAA | |
| SCHEMBL30470914 | 0.76 | MGAM (0.53) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A | |
| SCHEMBL1747926 | 0.76 | DYRK1A (0.49) | IDO1SMN1; SMN2NPSR1LOXL2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100718-B1 | ANTI-INFLAMMATORY PRODUCTS DERIVED FROM METHYLENEDIPHOSPHONIC ACID, AND PROCESS FOR THEIR PREPARATION | SANOFI S.A. (FR) | 1987-10-14 | — | — | EP | disclosed |
| EP-0100718-A1 | Anti-inflammatory products derived from methylenediphosphonic acid, and process for their preparation | SANOFI S.A. (FR) | 1984-02-15 | — | — | EP | disclosed |