Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778531 | 0.89 | TSHR (0.56) | TSHRALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2162442 | 0.81 | TSHR (0.50) | TSHRALOX15HPGDHSD17B10ALDH1A1 | |
| SCHEMBL69881 | 0.78 | — | — | |
| SCHEMBL11521596 | 0.77 | CYP3A4 (0.52) | TSHRALOX15HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10978453 | 0.76 | TSHR (0.45) | TSHRALOX15HPGDHSD17B10ALDH1A1 | |
| SCHEMBL9812315 | 0.74 | CYP1A2 (0.51) | TSHRCYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL31438320 | 0.74 | CYP1A2 (0.51) | TSHRCYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL3480074 | 0.74 | ALOX15 (0.58) | TSHRALOX15HPGDHSD17B10ALDH1A1 | |
| SCHEMBL31339525 | 0.73 | ALOX15 (0.53) | TSHRALOX15HPGDHSD17B10ALDH1A1 | |
| SCHEMBL11205285 | 0.73 | ALOX15 (0.53) | TSHRALOX15HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087295-B1 | WATER TREATMENT METHODS AND COMPOSITIONS | HOUSEMAN LIMITED (GB) | 1986-12-10 | — | — | EP | claimed |
| EP-0087295-A1 | Water treatment methods and compositions | HOUSEMAN LIMITED (GB) | 1983-08-31 | — | — | EP | claimed |
| EP-0115922-B1 | CONTROL OF LEGIONELLA PNEUMOPHILA IN WATER SYSTEMS | BTP COCKER CHEMICALS LIMITED (GB) | 1987-07-08 | — | — | EP | disclosed |
| EP-0087295-B1 | WATER TREATMENT METHODS AND COMPOSITIONS | HOUSEMAN LIMITED (GB) | 1986-12-10 | — | — | EP | disclosed |
| EP-0087295-A1 | Water treatment methods and compositions | HOUSEMAN LIMITED (GB) | 1983-08-31 | — | — | EP | disclosed |