Isopropylbenzene

Isopropylbenzene

SCHEMBL10787308

C=CC(=O)Oc1ccccc1.CC(C)c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 1/20 0.44
XBP1 P17861 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HCAR2 Q8TDS4 1/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 1/20 0.42
PTGS1 P23219 1/20 0.41
NPY5R Q15761 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
CNR2 P34972 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRA P10827 1/20 0.39
ELANE P08246 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4596363 0.87 THRB (0.54) THRBHPGDXBP1NPC1RAB9A
Acrylic Acid SCHEMBL3913076 0.85 THRB (0.55) THRBATML3MBTL1HPGDLMNA
Hydrogen Peroxide SCHEMBL28479331 0.85 THRB (0.58) THRBATML3MBTL1HPGDMAPT
SCHEMBL28916 0.85 THRB (0.58) THRBATML3MBTL1HPGDMAPT
Fluoromethane SCHEMBL27972327 0.83 THRB (0.53) THRBATML3MBTL1HPGDMAPT
SCHEMBL30209195 0.83 THRB (0.56) THRBATML3MBTL1HPGDRAB9A
SCHEMBL28429842 0.83 THRB (0.56) THRBATML3MBTL1HPGDMAPT
SCHEMBL28968163 0.83 THRB (0.56) THRBATML3MBTL1HPGDMAPT
SCHEMBL11576296 0.83 THRB (0.56) THRBATML3MBTL1HPGDMAPT
Ethylene SCHEMBL28842231 0.83 THRB (0.56) THRBATML3MBTL1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107065-B1 PRECURLED FLEXOGRAPHIC PRINTING PLATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-19 EP disclosed
EP-0064565-B1 PROCESS FOR BROMINE SURFACE TREATMENT OF PHOTOSENSITIVE ELASTOMERIC FLEXOGRAPHIC PRINTING PLATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-11 EP disclosed
EP-0064564-B1 PROCESS FOR SURFACE TREATMENT OF FLEXOGRAPHIC PRINTING PLATES CONTAINING BUTADIENE/ACRYLONITRILE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-28 EP disclosed
EP-0058737-B1 Flexographic printing plates containing blended adhesives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-15 EP disclosed
US-4478931-A POSTEXPOSURE OF ELASTOMER TO ACTINIC RADIATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-23 US disclosed
EP-0107065-A2 Precurled flexographic printing plate E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-02 EP disclosed
US-4415649-A ACRYLONITRILE-BUTADIENE COPOLYMER, UNSATURATED COMPOUND, AND FREE RADICAL CATALYST BONDED TO SUPPORT BY BLEND OF POLYESTER,-URETHANE OR -AMIDE E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-15 US disclosed
US-4400459-A Process for bromine surface treatment of photosensitive elastomeric flexographic printing plates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-23 US disclosed
US-4400460-A Process for surface treatment of flexographic printing plates containing butadiene/acrylonitrile copolymers E. I. DU PONT DE NEMOURS AND COMPAMY (US) 1983-08-23 US disclosed
EP-0064565-A1 Process for bromine surface treatment of photosensitive elastomeric flexographic printing plates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-17 EP disclosed
EP-0064564-A1 Process for surface treatment of flexographic printing plates containing butadiene/acrylonitrile copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-17 EP disclosed
EP-0058737-A1 Flexographic printing plates containing blended adhesives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-01 EP disclosed
US-4050941-A PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US disclosed