Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | XIAP | P98170 | 1/20 | 0.64 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | ANPEP | P15144 | 3/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.56 |
| ▸ | KIF11 | P52732 | 4/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.53 |
| ▸ | LAP3 | P28838 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homophenylalanine SCHEMBL44311 | 1.00 | ALPI (0.64) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL130567 | 1.00 | ALPI (0.64) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL44312 | 1.00 | ALPI (0.64) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL28287974 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL28594537 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL1245414 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL1026468 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL2305748 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL28286602 | 0.98 | ALPI (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Homophenylalanine SCHEMBL1318113 | 0.93 | ALPI (0.56) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658169-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | Yeda Research and Development Co. Ltd (IL) | 2020-06-03 | — | — | EP | disclosed |
| WO-2019021284-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2019-01-31 | — | — | WO | disclosed |
| EP-3046929-A1 | ERK-DERIVED PEPTIDES AND USES THEREOF | Yeda Research and Development Co., Ltd. (IL) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015040609-A1 | ERK-DERIVED PEPTIDES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-03-26 | — | — | WO | disclosed |
| WO-2011005069-A1 | A SYSTEM FOR PRODUCING L-HOMOPHENYLALANINE AND A PROCESS FOR PRODUCING L-HOMOPHENYLALANINE | UNIVERSITI SAINS MALAYSIA (MY) | 2011-01-13 | — | — | WO | disclosed |