Homophenylalanine

Homophenylalanine

SCHEMBL44311

N[C@@H](CCc1ccccc1)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.64
PKM P14618 1/20 0.64
PTGS1 P23219 1/20 0.64
XIAP P98170 1/20 0.64
SLC7A5 Q01650 1/20 0.64
GRIK1 P39086 3/20 0.62
ERAP1 Q9NZ08 4/20 0.56
ANPEP P15144 3/20 0.56
ERAP2 Q6P179 3/20 0.56
KIF11 P52732 4/20 0.55
SLC1A3 P43003 1/20 0.55
SLC1A2 P43004 1/20 0.55
SLC1A1 P43005 1/20 0.55
GRIA1 P42261 1/20 0.53
GRIA2 P42262 1/20 0.53
GRIA3 P42263 1/20 0.53
GRIA4 P48058 1/20 0.53
GRIK2 Q13002 1/20 0.53
GRIK3 Q13003 1/20 0.53
LAP3 P28838 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homophenylalanine SCHEMBL130567 1.00 ALPI (0.64) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL44312 1.00 ALPI (0.64) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL1078733 1.00 ALPI (0.64) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL28287974 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL28594537 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL1245414 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL1026468 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL2305748 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL28286602 0.98 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Homophenylalanine SCHEMBL1318113 0.93 ALPI (0.56) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14815 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
CN-122010656-A Application of oxyalkylisourea in introducing methyl and isotopically-labeled methyl 陕西师范大学 2026-05-12 CN claimed
CN-122011091-A Polypeptide compound, preparation method, pharmaceutical composition and application thereof 中山莱博瑞辰生物医药有限公司 2026-05-12 CN claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4717776-A2 POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS Ohio State Innovation Foundation (US) 2026-04-01 EP claimed
US-12590123-B2 Compounds and methods for treating cancer, viral infections, and allergic conditions WASHINGTON UNIVERSITY (US) 2026-03-31 US claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 US claimed
US-12545938-B1 Method for efficiently producing L-homophenylalanine and strain producing L- homophenylalanine JIANGNAN UNIVERSITY (CN) 2026-02-10 US claimed
US-20260035408-A1 WKYMVm peptide analogues having six residues and uses thereof RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR) 2026-02-05 US claimed
EP-0332008-A2 Peptide-like aminoacid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-09-13 EP claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0310918-A2 Peptide-like amino-acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-04-12 EP claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0310012-A2 Process for the preparation of optically pure homophenyl alanine HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0253199-A2 Process for the biocatalytic conversion of substrates having a poor solubility in aqueous solutions HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-20 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed