Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786517 | 0.89 | NPC1 (0.43) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL11134228 | 0.87 | MEN1 (0.42) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL10786088 | 0.87 | MEN1 (0.43) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL10908649 | 0.86 | NPC1 (0.45) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL10786095 | 0.82 | MEN1 (0.43) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL10783350 | 0.81 | RAB9A (0.48) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL11242482 | 0.81 | NPC1 (0.45) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL10783997 | 0.80 | MAPT (0.47) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL11242054 | 0.79 | NPC1 (0.44) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL7605796 | 0.78 | MEN1 (0.50) | MEN1KMT2ANPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116728-B1 | COMPOSITION ACTIVE AGAINST MITES, WHITEFLY AND THRIPS, PHARMACEUTICAL COMPOSITION, AND NEW BENZOYLUREAU COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-08-12 | — | — | EP | disclosed |
| US-4567295-A | Composition active against mites, whitefly and thrips, pharmaceutical composition, and new benzoylurea compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-01-28 | — | — | US | disclosed |