SCHEMBL10790230

SCHEMBL10790230

CNc1ccc(Nc2ccc(C(=O)O)cc2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.58
▸ MEN1 O00255 5/20 0.58
▸ P2RY4 P51582 1/20 0.56
▸ MAPT P10636 8/20 0.55
▸ MAPK1 P28482 5/20 0.55
▸ RAB9A P51151 5/20 0.55
▸ L3MBTL1 Q9Y468 3/20 0.55
▸ NPC1 O15118 3/20 0.55
▸ NPSR1 Q6W5P4 3/20 0.55
▸ HKDC1 Q2TB90 3/20 0.55
▸ HTT P42858 2/20 0.55
▸ HK1 P19367 1/20 0.55
▸ CDC25A P30304 1/20 0.55
▸ CDC25B P30305 1/20 0.55
▸ CDC25C P30307 1/20 0.55
▸ CYP1A2 P05177 1/20 0.53
▸ TSHR P16473 1/20 0.53
▸ TDP1 Q9NUW8 3/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.49
▸ EGFR P00533 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10793604 0.93 P2RY4 (0.62) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL10789018 0.91 P2RY4 (0.60) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL30922379 0.87 MAPT (0.59) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL139752 0.87 MAPT (0.59) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL31150807 0.87 MAPT (0.59) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL10791991 0.86 MAPT (0.64) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL10790208 0.85 KMT2A (0.61) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL29352991 0.85 KMT2A (0.61) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL10789007 0.83 MAPT (0.57) KMT2AMEN1P2RY4MAPTMAPK1
SCHEMBL92477 0.82 P2RY2 (0.55) KMT2AMEN1P2RY4MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 — — US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 — — US disclosed
EP-3558235-B1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION OREAL (FR) 2021-09-08 — — EP disclosed
WO-2018115337-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2018-06-28 — — WO disclosed
EP-0140620-B1 SILANE ANTHRAQUINONE DYES, COMPOSITE PIGMENTS OBTAINABLE THEREFROM, AND PROCESSES FOR PREPARING THE SAME Montedison S.p.A. (IT) 1987-08-12 — — EP disclosed
EP-0140620-A1 Silane anthraquinone dyes, composite pigments obtainable therefrom, and processes for preparing the same Montedison S.p.A. (IT) 1985-05-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 KMT2A 2181/4885MEN1 2794/4885P2RY4 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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