CUTA — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to CUTA by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
n-3 Polysaturated Fatty Acids-rich Diet in Psoriasis	PHASE4	COMPLETED
STUDY TO ASSESS THE LONG-TERM SAFETY OF EXTINA (KETOCONAZOLE) FOAM, 2%	PHASE4	COMPLETED
The Technique of Skin Stretching for Acute Burn Treatment and Scar Reconstruction	PHASE3	COMPLETED
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer	PHASE1/PHASE2	COMPLETED
Safety and Pharmacokinetics of GNR-038 in Healthy Volunteers	PHASE1	COMPLETED
Fractional Co2 Laser Versus Microbotox Injection in the Treatment of Wide Facial Pores: A Split Face Comparative Study	PHASE1	UNKNOWN
Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE)	nan	COMPLETED
Identification of Epidermal Signatures in Patients With Atopic Dermatitis	nan	UNKNOWN
The Skin Microbiota in Skin Disease and Eczema	nan	ENROLLING_BY_INVITATION
Proteomic Analysis of Sweat in Cutaneous Conditions	nan	WITHDRAWN
Efficacy of Vinh Wellness Collagen on Skin Health	nan	COMPLETED
Hand Sanitizer Effects on the Skin Barrier	nan	UNKNOWN
Dressing Versus Glue (2-Octyl Cyanoacrylate) for Coverage of the Skin Incision After Closure During Cesarean Delivery	nan	WITHDRAWN
MD Auralia (HA Filler) in Treatment of Nasolabial Wrinkles	nan	COMPLETED
Study of PCC1 for Skin Rejuvenation	nan	COMPLETED
Retention of Vernix Caseosa in Newborns for Primary Prevention of Atopic Dermatitis	nan	NOT_YET_RECRUITING
A Study to Assess the Local Cutaneous and Ocular Tolerance of Three Developmental Facial Skin-care Formulations.	nan	COMPLETED
ADRN Barrier/Immunoprofiling Exploratory Pilot Study	nan	COMPLETED
Evaluation of Oral Collagen Peptides on Skin Barrier Function in Women	nan	RECRUITING
Efficacy of Gel With Ecological Extra Virgin Olive Oil in Peristomal Skin Hygiene	nan	COMPLETED
Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin	nan	UNKNOWN
Electrical Stimulation and Expression of VEGF and NO in Diabetic Foot Ulcer	nan	COMPLETED
Comparative Study of Low-Energy 1064nm Laser and DPL in Rosacea Treatment	nan	COMPLETED
The Gut-Skin Axis Integrity in Psoriatic Patients	nan	UNKNOWN
Efficacy Evaluation and Cutaneous Acceptability of the Lipikar Med Product on Subjects With Atopic Dermatitis	nan	COMPLETED
Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Barrier Repair	nan	ACTIVE_NOT_RECRUITING
Impact of Timing of Wound Dressing Removal After Cesarean Section	nan	COMPLETED
New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat	nan	UNKNOWN
Interactions Between Skincare Product Ingredients and the Skin Microbiome	nan	COMPLETED
Skin Reactions Related to Thoracic Implantable Chamber Dressings	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a CUTA binder may also engage these)

Protein	Name	Similarity
Q9CQ89	—	1.000	Q9CQ89 →
Q6MGD0	—	1.000	Q6MGD0 →
P69678	—	0.998	P69678 →
Q66KY3	—	0.978	Q66KY3 →
P47823	—	0.959	P47823 →
Q6ZT62	—	0.958	Q6ZT62 →
EIF2B5	Translation initiation factor eIF2B subunit epsilon	0.958	landscape →
Q3B7U9	—	0.958	Q3B7U9 →
O35465	—	0.958	O35465 →
Q9D2Q2	—	0.957	Q9D2Q2 →
Q14CH1	—	0.956	Q14CH1 →
Q9XT50	—	0.956	Q9XT50 →
Q5NVK5	—	0.955	Q5NVK5 →
Q8BGG6	—	0.955	Q8BGG6 →
Q496Y0	—	0.955	Q496Y0 →
A0JPF9	—	0.954	A0JPF9 →
MAP4K2	Mitogen-activated protein kinase kinase kinase kinase 2	0.954	landscape →
Q8CHW4	—	0.953	Q8CHW4 →
Q5EA80	—	0.953	Q5EA80 →
A5A779	—	0.953	A5A779 →
P70218	—	0.953	P70218 →
TRMT1	tRNA (guanine(26)-N(2))-dimethyltransferase	0.953	landscape →
Q8MIR4	—	0.952	Q8MIR4 →
Q9UJY4	—	0.952	Q9UJY4 →
A4IHY0	—	0.952	A4IHY0 →
Q5RCE5	—	0.952	Q5RCE5 →
P70268	—	0.952	P70268 →
Q5S6T3	—	0.952	Q5S6T3 →
D2GU20	—	0.952	D2GU20 →
Q3TX08	—	0.952	Q3TX08 →