Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10789519 | 0.99 | CHRM2 (0.42) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL10812019 | 0.84 | CHRM2 (0.39) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL10812402 | 0.84 | ALDH1A1 (0.41) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL18138718 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL10813008 | 0.80 | MEN1 (0.41) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL10816482 | 0.80 | MEN1 (0.46) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL27758119 | 0.80 | MEN1 (0.46) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL10812602 | 0.78 | MEN1 (0.46) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL27758106 | 0.78 | MEN1 (0.44) | MAOAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10811891 | 0.77 | BDKRB1 (0.38) | CHRM2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4694003-A | Method of treating depression with 5-(aminoalkyl)-11-phenyl-5H-dibenzo(b,e)(1,4) diazepines | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-09-15 | — | — | US | disclosed |