Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680857 | 0.82 | CASP1 (0.45) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL248893 | 0.81 | — | — | |
| SCHEMBL19672930 | 0.80 | MEN1 (0.38) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL9129459 | 0.80 | MEN1 (0.38) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL20793437 | 0.80 | MEN1 (0.38) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL4684975 | 0.80 | MEN1 (0.41) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL9547232 | 0.80 | MAPT (0.46) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL2343808 | 0.80 | MEN1 (0.38) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL13055388 | 0.79 | MAPT (0.42) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL9486696 | 0.79 | MAPT (0.42) | MEN1KMT2AMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656165-A | Aminomethyl penem compounds | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |