Terephthalic Acid

Terephthalic Acid

SCHEMBL107909

O=C([O-])c1ccc(C(=O)[O-])cc1.[K+].[K+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.68
CA1 P00915 17/20 0.68
CA4 P22748 1/20 0.63
MAPT P10636 1/20 0.47
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL31095057 1.00 CA2 (0.68) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL7910695 0.97 CA2 (0.65) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL9930546 0.97 CA2 (0.65) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL15641843 0.97 CA2 (0.74) CA2CA1CA4MAPT
Terephthalic Acid SCHEMBL2841686 0.93 CA2 (0.78) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL1535442 0.93 CA2 (0.68) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL166041 0.93 CA2 (0.68) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL6665082 0.93 CA2 (0.68) CA2CA1CA4TP53TSHR
Terephthalic Acid SCHEMBL20704875 0.93 CA2 (0.68) CA2CA1CA4MAPTTP53
Terephthalic Acid SCHEMBL1006722 0.93 CA2 (0.68) CA2CA1CA4MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735413-A1 CRYSTALLIZATION METHOD FOR PURIFIED TEREPHTHALIC ACID DePoly SA (CH) 2026-05-06 EP claimed
CN-119873968-A Embedded-based materials and processes for softening water 罗伯特·博世有限公司 2025-04-25 CN claimed
WO-2025000111-A1 CRYSTALLIZATION METHOD FOR PURIFIED TEREPHTHALIC ACID DEPOLY SA (CH) 2025-01-02 WO claimed
CN-119186522-A Aerogel-porous carbon sphere composite material and preparation method and application thereof 中国烟草总公司郑州烟草研究院 2024-12-27 CN claimed
CN-118693224-A Negative pole piece, battery and electric equipment 宁德时代新能源科技股份有限公司 2024-09-24 CN claimed
CN-114591727-B Organic long-afterglow luminescent material, preparation and application 中国科学院上海有机化学研究所 2024-06-28 CN claimed
CN-118217994-A High-activity water gas shift reaction catalyst and preparation method thereof 吉首大学 2024-06-21 CN claimed
CN-115724713-B Method for preparing dipotassium terephthalate 沈阳工业大学 2024-04-12 CN claimed
CN-117362919-A PEEK/UiO-66 composite material and preparation method and application thereof 中国科学院兰州化学物理研究所 2024-01-09 CN claimed
US-11769881-B1 Ion-based electrochemical cell formulations and methods of preparation thereof ORUGANTY SRIGOURI (US) 2023-09-26 US claimed
US-4430511-A POTASSIUM BENZOATES, DISPROPORTIONATION, DIPOTASSIUM TEREPHTHALATE, PRECIPITATION, TERPHENYL, LOW VISCOSITY SLURRY PHILLIPS PETROLEUM COMPANY (US) 1984-02-07 US claimed
US-4409113-A Synthetic hot forging lubricants and process PENNWALT CORPORATION (US) 1983-10-11 US claimed
EP-0078361-A1 Synthetic hot forging lubricants and process PENNWALT CORPORATION (US) 1983-05-11 EP claimed
US-4368283-A HEAT RESISTANT MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1983-01-11 US claimed
US-4345098-A HYDROLYSIS, OXIDATION, ISOMERIZATION OCCIDENTAL RESEARCH CORPORATION (US) 1982-08-17 US claimed
US-4271316-A Process for the continuous rearrangement of alkali metal salts of aromatic carboxylic acids RHONE-POULENC INDUSTRIES (FR) 1981-06-02 US claimed
US-4212991-A Single-stage process for the preparation of terephthalic acid RHONE-POULENC INDUSTRIES (FR) 1980-07-15 US claimed
US-4200586-A Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds PHILLIPS PETROLEUM COMPANY (US) 1980-04-29 US claimed
US-4092230-A FROM POTASSIUM HYDROGEN TEREPHTHALATE OR TEREPHTHALONITRILE IN PRESENCE OF POTASSIUM SALT SUNTECH, INC. (US) 1978-05-30 US claimed
US-3952052-A Process for producing alkali metal salts of aromatic polycarboxylic acids PHILLIPS PETROLEUM COMPANY (US) 1976-04-20 US claimed