Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792163 | 1.00 | NPC1 (0.38) | NPC1RAB9AHPGDTSHRALDH1A1 | |
| SCHEMBL10794249 | 0.78 | ACACB (0.37) | HPGDTSHRALDH1A1KMT2AMAPT | |
| SCHEMBL10790514 | 0.77 | RAB9A (0.38) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL10794084 | 0.77 | POLB (0.39) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL10790510 | 0.77 | RAB9A (0.38) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL10794080 | 0.77 | POLB (0.39) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL10790091 | 0.76 | ACACB (0.39) | HPGDKMT2AMAPTLMNAACACB | |
| SCHEMBL10790098 | 0.76 | ACACB (0.39) | HPGDKMT2AMAPTLMNAACACB | |
| SCHEMBL10794831 | 0.76 | ACACB (0.40) | HPGDKMT2AMAPTLMNAACACB | |
| SCHEMBL10790802 | 0.73 | ACACB (0.39) | KMT2AMAPTLMNASMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647698-A | Novel compositions | SANDOZ LTD. (US) | 1987-03-03 | — | — | US | disclosed |