⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707599 | 0.67 | CYP2C9 (0.32) | — | |
| SCHEMBL8415432 | 0.67 | — | — | |
| SCHEMBL2389180 | 0.65 | TSHR (0.36) | — | |
| SCHEMBL834 | 0.65 | — | — | |
| SCHEMBL52710 | 0.63 | — | — | |
| SCHEMBL3705756 | 0.62 | — | — | |
| SCHEMBL23929779 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL10701634 | 0.62 | — | — | |
| SCHEMBL2815843 | 0.62 | TSHR (0.38) | — | |
| SCHEMBL27602790 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075180-B | Immunomodulatory compounds and anti-tumor applications thereof | 上海科技大学 | 2024-04-05 | — | — | CN | claimed |
| CN-113582980-B | Compound based on heterocyclic ring and glutarimide skeleton and application thereof | 上海科技大学 | 2023-11-24 | — | — | CN | claimed |
| US-20230303539-A1 | IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2023-09-28 | — | — | US | claimed |
| EP-4198030-A1 | IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF | Shanghaitech University (CN) | 2023-06-21 | — | — | EP | claimed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | claimed |
| CN-114075180-A | Immunomodulatory compounds and their anti-tumor applications | 上海科技大学 | 2022-02-22 | — | — | CN | claimed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | claimed |
| CN-113582980-A | Compound based on heterocyclic ring and glutarimide framework and application thereof | 上海科技大学 | 2021-11-02 | — | — | CN | claimed |
| US-20120010256-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB | 2012-01-12 | — | — | US | claimed |
| JP-4789934-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| US-5278160-A | Treating aggressive behavior | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-11 | — | — | US | claimed |
| US-5270316-A | Condensed purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| US-5254552-A | Cognition activators, psychological disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-19 | — | — | US | claimed |
| US-5106849-A | Treating anxiety, depression, psychoses | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-21 | — | — | US | claimed |
| EP-0423805-A2 | Condensed purine derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1991-04-24 | — | — | EP | claimed |
| US-5010078-A | Anxiolytic, antidepressant agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| US-4921958-A | ANXIOLYTIC AGENTS, ANTIDEPRESSANTS, ANTIPSYCHOTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-05-01 | — | — | US | claimed |
| EP-0343961-A2 | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-11-29 | — | — | EP | claimed |
| US-4882432-A | ANTIDEPRESSANT, ANTIPSYCHOTIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-11-21 | — | — | US | claimed |
| US-4873331-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-10-10 | — | — | US | claimed |