Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 10/20 | 0.57 |
| ▸ | NPY1R | P25929 | 5/20 | 0.57 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792547 | 1.00 | NPY4R (0.57) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL30434218 | 0.94 | NPY4R (0.59) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| Hydrochloric Acid SCHEMBL30380134 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| Hydrochloric Acid SCHEMBL29726986 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| Hydrochloric Acid SCHEMBL29508688 | 0.92 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL30379845 | 0.91 | NPY4R (0.63) | NPY4RNPY1RNPY2RNPY5RERAP2 | |
| Hydrochloric Acid SCHEMBL29508677 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RERAP2 | |
| Hydrochloric Acid SCHEMBL30379307 | 0.90 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RERAP2 | |
| SCHEMBL21782583 | 0.88 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RGNAI3 | |
| SCHEMBL16263595 | 0.88 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661453-A | FROM CULTURED RAT PROSTATE ADENOCARCINOMA CELLS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1987-04-28 | — | — | US | disclosed |