Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.46 |
| ▸ | NPY1R | P25929 | 7/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.37 |
| ▸ | NPY2R | P49146 | 4/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263595 | 0.88 | NPY4R (0.48) | NPY4RNPY1RSIRT6SIRT1NPY5R | |
| SCHEMBL10792547 | 0.88 | NPY4R (0.57) | NPY4RNPY1RSIRT6SIRT1NPY5R | |
| SCHEMBL10792564 | 0.88 | NPY4R (0.57) | NPY4RNPY1RSIRT6SIRT1NPY5R | |
| SCHEMBL21782631 | 0.87 | ERAP2 (0.43) | SIRT6SIRT1ERAP2LNPEPERAP1 | |
| SCHEMBL20620363 | 0.86 | NPY4R (0.48) | NPY4RNPY1RSIRT6SIRT1NPY5R | |
| SCHEMBL21782661 | 0.82 | NPY4R (0.41) | NPY4RNPY1RSIRT1NPY5RNPY2R | |
| SCHEMBL21782708 | 0.82 | GNAI3 (0.35) | NPY4RNPY1RSIRT6SIRT1NPY5R | |
| SCHEMBL17015152 | 0.82 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21782578 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16263594 | 0.81 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |