Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790277 | 0.90 | MME (0.46) | MMEACEECE1FOLH1 | |
| SCHEMBL7369702 | 0.83 | ACE (0.58) | MMEACEECE1MMEL1 | |
| SCHEMBL10792960 | 0.81 | LTA4H (0.46) | MMEACEECE1 | |
| SCHEMBL9069494 | 0.81 | ACE (0.61) | MMEACEECE1MMEL1 | |
| SCHEMBL7367809 | 0.80 | ACE (0.70) | MMEACEECE1MMEL1 | |
| SCHEMBL7367811 | 0.80 | ACE (0.70) | MMEACEECE1MMEL1 | |
| SCHEMBL7318461 | 0.80 | ACE (0.70) | MMEACEECE1MMEL1 | |
| SCHEMBL10791111 | 0.79 | ACE (0.68) | MMEACEECE1MMEL1 | |
| SCHEMBL10789074 | 0.79 | ACE (0.68) | MMEACEECE1MMEL1 | |
| SCHEMBL7362944 | 0.77 | ACE (0.65) | MMEACEECE1MMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |