Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.56 |
| ▸ | LSS | P48449 | 2/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360200 | 0.82 | BCHE (0.69) | BCHEACHELSSTHRATHRB | |
| SCHEMBL11718751 | 0.82 | BCHE (0.52) | BCHEACHETHRATHRBSLC2A1 | |
| Hydrochloric Acid SCHEMBL11672602 | 0.80 | BCHE (0.58) | BCHEACHETHRATHRBSLC2A1 | |
| SCHEMBL5727095 | 0.80 | KDM4E (0.64) | BCHEACHELSSKDM4ESMN1; SMN2 | |
| SCHEMBL7431876 | 0.79 | LSS (0.53) | LSSTHRBKDM4ESMN1; SMN2HRH2 | |
| SCHEMBL9365154 | 0.79 | KDM4E (0.76) | BCHEACHELSSTHRATHRB | |
| SCHEMBL10797121 | 0.78 | FDPS (0.47) | BCHEACHEKDM4ESMN1; SMN2LTA4H | |
| SCHEMBL8769969 | 0.78 | TP53 (0.68) | SMN1; SMN2 | |
| SCHEMBL11715650 | 0.78 | BCHE (0.53) | BCHEACHETHRATHRBSLC2A1 | |
| SCHEMBL9361193 | 0.78 | LSS (0.59) | LSSKDM4ESMN1; SMN2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645779-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-02-24 | — | — | US | disclosed |
| EP-0114410-B1 | SUBSTITUTED ALPHA-(ETHYL)-ALPHA-(PHENYL)-(OMEGA-(DIALKYLAMINO)-ALKOXY)-BENZYL ALCOHOLS, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION, AS WELL AS MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-05-14 | — | — | EP | disclosed |
| EP-0114410-A1 | Substituted alpha-(ethyl)-alpha-(phenyl)-(omega-(dialkylamino)-alkoxy)-benzyl alcohols, their acid addition salts and quaternary salts, process for their preparation, as well as medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-08-01 | — | — | EP | disclosed |