Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795577 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10824092 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10795787 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10613317 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10795801 | 0.81 | L3MBTL1 (0.57) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10799238 | 0.80 | KMT2A (0.44) | SMN1; SMN2L3MBTL1TDP1MAPTKMT2A | |
| SCHEMBL10613284 | 0.80 | L3MBTL1 (0.57) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10794878 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10824085 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL10795592 | 0.74 | KMT2A (0.57) | SMN1; SMN2L3MBTL1TDP1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652666-A | PLANT SAFENING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |