Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473714 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL827863 | 0.81 | TSHR (0.70) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL29387332 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL28614232 | 0.78 | TSHR (0.71) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL42787 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8144263 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL2036542 | 0.77 | TSHR (0.59) | ALDH1A1TSHRMAPTKDM4EMEN1 | |
| SCHEMBL4627198 | 0.76 | TSHR (0.63) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| SCHEMBL5078844 | 0.76 | TSHR (0.63) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL28046886 | 0.76 | ALDH1A1 (0.96) | ALDH1A1TSHRMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086472-B1 | CATALYST FOR THE POLYMERIZATION OF OLEFINS | Montedison S.p.A. (IT) | 1987-05-20 | — | — | EP | disclosed |
| US-4473660-A | COORDINATION CATALYST-CONTAINING ALKYL-ALUMINUM COMPOUND, ELECTRON DONOR, TITANIUM COMPOUND AND ESTER ON MAGNESIUM HALIDE SUPPORT | MONTEDISON S.P.A. (IT) | 1984-09-25 | — | — | US | disclosed |
| EP-0086472-A2 | Catalyst for the polymerization of olefins | Montedison S.p.A. (IT) | 1983-08-24 | — | — | EP | disclosed |
| EP-0045977-A2 | Components and catalysts for the polymerization of olefins | Montedison S.p.A. (IT) | 1982-02-17 | — | — | EP | disclosed |