Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2748786 | 0.82 | ALDH1A1 (0.55) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10794880 | 0.82 | ALDH1A1 (0.55) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL19296595 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL15451589 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL113313 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL901228 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL16477727 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL26689720 | 0.78 | TSHR (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14968000 | 0.76 | TSHR (0.50) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL1069512 | 0.76 | TSHR (0.50) | TSHRMEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4716226-A | Optically active 4-carbalkoxy-2-azetidinones | ROUSSEL UCLAF (FR) | 1987-12-29 | — | — | US | disclosed |